Healthcare · Applied AI

PathAI

AI-assisted digital pathology. Expert judgment at the centre.

PathAI connects whole-slide imaging, three AI capabilities and pathologist-led review for colorectal adenocarcinoma, from case intake to a finalized report.

PathAI interactive demo

Draw a region, then run the demo to reveal four tissue classes.

Synthetic slide · precomputed result. This promotional demo uses predefined overlays, without live AI inference or uploaded slides. The full platform’s nucleus analysis, tumour–stroma ratio and expert approval workflow are outside this demonstration.

Three integrated AI capabilities.

Region detection

Coarse analysis proposes tumour-bearing regions on the whole-slide image, giving the pathologist a starting point for closer inspection.

Tissue segmentation

Detailed analysis distinguishes tumour glands, tumour stroma, normal glands and normal stroma, with background handled separately.

Nucleus analysis

Individual nuclei are identified and measured, producing counts, area, shape and density information alongside tissue-level findings.

Histology image with coloured overlays showing tissue segmentation in the PathAI prototype.
Development prototype: tissue segmentation overlays displayed on the original slide.
From intake to report

The pathologist stays in control.

  1. Create a case

    Organize patient and case information, upload whole-slide images and resume interrupted uploads.

  2. Run AI analysis

    Process suggested or manually selected regions, with visible job progress and separate tissue and nucleus results.

  3. Inspect and correct

    Compare overlays with the original slide. Edit annotations, add notes, and approve or reject findings.

  4. Complete the report

    Request a second opinion when needed, then finalize the professional report and retain the case history.

PathAI prototype viewer with tissue analysis, region details and controls to approve or reject findings.
Development prototype: inspect AI findings, add review notes and approve or reject results.

Measurements with context.

PathAI brings tissue areas, object counts and nucleus morphology into region and case summaries. The tumour–stroma ratio is calculated from segmented tumour-gland and tumour-stroma areas.

Measurements retain analysis coverage and model provenance, so the pathologist can assess both the result and the tissue it represents. These outputs support expert interpretation within the review workflow.

Platform engineering

Controlled collaboration

Access follows institutional membership, role and case assignment. An invited external reviewer can provide a second opinion, with their annotations retained separately from the primary record.

Traceable processing

Persistent analysis jobs support progress tracking and recovery. Versioned models, annotation revisions and audit history connect results to the processing and review actions behind them.

Project milestone · 31 August 2026

A working prototype.
Evaluated with KCCG.

PathAI is an integrated research prototype developed by ITAS with the Clinical Center of Montenegro. Technical verification was followed by a final operational evaluation on 31 August 2026, documented in a joint assessment signed by three participating pathologists.

The positive assessment highlighted tumour-region detection, quantitative analysis including tumour–stroma ratio, and the ability to inspect and correct AI findings. Experts recommended further refinement in heterogeneous tumour regions and validation on a larger, more diverse case set.

Broader clinical validation, prospective studies of diagnostic performance and time savings, and further institutional integration are next steps before wider routine diagnostic use.

Project collaboration

ITAS
Developer

IT Advanced Services d.o.o.

Clinical Center of Montenegro
Collaborating institution

Clinical Center of Montenegro

Innovation Fund of Montenegro
Financial support

Innovation Fund of Montenegro

AI System for Pathological Analysis of Adenocarcinoma (PathAI) · CGI-017-24

Bring your expertise.

Talk to us about applying AI to your field.

NTP, Bulevar Mihaila Lalića · Podgorica, Montenegroinfo@itas.ai

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